منابع مشابه
B and T lymphocytes in primary immunodeficiency disease in man.
B- and T-cell populations in 32 patients with different forms of primary immunodeficiency disease were studied. The B-cells in peripheral blood were investigated with respect to surface immunoglobulins by means of immunofluorescence. The T-cell function was studied utilizing quantitation of proliferative response to phytochemagglutinin (PHA)(1) and delayed allergy to various antigens. In 10 pat...
متن کاملWnt signaling in B and T lymphocytes.
Wnt signaling has been shown to be critical for proper embryonic development as well as growth regulation of certain adult tissues. Defects in Wnt pathways have additionally been associated with a number of human cancers. However, it is only recently that a role for Wnts in the immune system has come to be appreciated. Wnts have now been shown to play significant roles in early stage developmen...
متن کاملAlpha chain disease.
The pathological and clinical features of alpha-chain disease, its immunological diagnosis, the structural abnormalities of the abnormal immunoglobulin A compared with those of proteins of gamma and mu heavy chains diseases, the course of the disease and its present treatment, the epidemiological factors involved and their influence on pathogenesis and finally, the relationship with the "Medite...
متن کاملSequences and repertoire of human T cell receptor alpha chain variable region genes in mature T lymphocytes
24 human T cell receptor alpha chain messages have been examined by cDNA sequence analysis and Southern blot. The data indicate that there are approximately 40 alpha chain T cell receptor variable gene segments, which can be divided into 12 families. Comparison of the J gene segments from the cDNAs to previously determined germline J alpha sequences places the number of J alpha gene segments ov...
متن کاملSurface Globulins of T and B Lymphocytes
The concept that lymphocytes recognize antigens by means of a surface receptor molecule of immunoglobulin (Ig) character has come to be widely accepted (1-3). Direct study of such receptors in the mouse by means of antiglobulin reagents labeled with either fuorescent (4, 5) or radioisotope (3, 6-8) markers has revealed a dense coating of surface immunoglobulins on nonthymus-derived or B lymphoc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1978
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1978.7